Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732149 | 0.99 | PSEN1 (0.37) | PSEN1KIF11SLC7A5FFAR1S1PR1 | |
| SCHEMBL7732585 | 0.96 | HTR2A (0.37) | KIF11SLC7A5FFAR1PPARGPPARA | |
| SCHEMBL7730566 | 0.95 | HTR2A (0.38) | KIF11SLC7A5FFAR1PPARGPPARA | |
| SCHEMBL7730438 | 0.94 | DAO (0.40) | PSEN1KIF11SLC7A5FFAR1S1PR1 | |
| SCHEMBL7729985 | 0.92 | KIF11 (0.38) | KIF11SLC7A5FFAR1MAOBCYP11B1 | |
| SCHEMBL7722564 | 0.92 | KIF11 (0.48) | KIF11MAOBCYP11B1CYP11B2HSD11B1 | |
| SCHEMBL7729765 | 0.91 | KIF11 (0.38) | KIF11SLC7A5FFAR1MAOBCYP11B1 | |
| SCHEMBL7735591 | 0.90 | DAO (0.39) | KIF11FFAR1S1PR1PPARGDAO | |
| SCHEMBL7735381 | 0.88 | KIF11 (0.47) | KIF11CYP11B1CYP11B2HSD11B1 | |
| SCHEMBL7729630 | 0.87 | KIF11 (0.39) | KIF11SLC7A5FFAR1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |