Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12389949 | 1.00 | HSD11B1 (0.35) | HSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12389943 | 0.97 | HSD11B1 (0.34) | HSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7741566 | 0.97 | HSD11B1 (0.34) | HSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7732828 | 0.97 | HSD11B1 (0.34) | HSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7733474 | 0.97 | HSD11B1 (0.34) | HSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7739168 | 0.97 | HSD11B1 (0.34) | HSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7739338 | 0.97 | HSD11B1 (0.34) | HSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7738780 | 0.97 | HSD11B1 (0.34) | HSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12389946 | 0.92 | HSD11B1 (0.39) | HSD11B1 | |
| SCHEMBL23829718 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990634-B1 | ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES | DAICEL CHEM (JP) | 2013-04-10 | — | — | EP | disclosed |
| US-6429314-B1 | USING 1,2-DICARBONYL DERIVATIVE OR ITS HYDROXY REDUCTIVE, OXYGEN, COBALT ACETATE METAL COMPOUND, AND N-HYDROXYPHTHALIMIDE OR OTHER IMIDE DERIVATIVE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-08-06 | — | — | US | disclosed |
| EP-0990634-A1 | ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES | Daicel Chemical Industries, Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |