Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | ACR | P10323 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2842657 | 0.94 | TSHR (0.61) | TSHRSLC6A3KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL5705966 | 0.91 | SLC6A3 (0.59) | TSHRSLC6A3KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL5706247 | 0.91 | SLC6A3 (0.59) | TSHRSLC6A3KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL4391331 | 0.89 | SLC6A3 (0.59) | TSHRSLC6A3KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2910803 | 0.89 | KDM4E (0.63) | TSHRSLC6A3KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL5706110 | 0.88 | TSHR (0.66) | TSHRSLC6A3KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL1283310 | 0.88 | TSHR (0.69) | TSHRSLC6A3KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8499927 | 0.86 | TSHR (0.51) | TSHRSLC6A3KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL4391361 | 0.86 | TSHR (0.67) | TSHRSLC6A3KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6439342 | 0.85 | SLC6A3 (0.72) | TSHRSLC6A3KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417291-B1 | CONDENSATION POLYMERIZATION AND ESTERIFICATION OF AROMATIC DIOL AND ESTER-FORMING MONOMER; ENDCAPPING WITH SALICYLIC ACID ESTER DERIVATIVE | TEIJIN LIMITED (JP) | 2002-07-09 | — | — | US | disclosed |