Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.46 |
| ▸ | KDR | P35968 | 4/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732103 | 0.95 | RAB9A (0.53) | RAB9ANPC1MAPTSMN1; SMN2NFKB1 | |
| SCHEMBL7732373 | 0.90 | TRPV1 (0.50) | RAB9ANPC1MAPTSMN1; SMN2NFKB1 | |
| SCHEMBL7733996 | 0.86 | NPC1 (0.50) | RAB9ANPC1MAPTSMN1; SMN2NFKB1 | |
| Trifluoroacetic Acid SCHEMBL7723297 | 0.85 | RAB9A (0.41) | RAB9ANPC1MAPTSMN1; SMN2NFKB1 | |
| SCHEMBL7735550 | 0.84 | TRPV1 (0.52) | RAB9ANPC1MAPTSMN1; SMN2NFKB1 | |
| Trifluoroacetic Acid SCHEMBL7733887 | 0.83 | RAB9A (0.39) | RAB9ANPC1MAPTSMN1; SMN2NFKB1 | |
| SCHEMBL7734013 | 0.82 | NPC1 (0.45) | RAB9ANPC1MAPTSMN1; SMN2NFKB1 | |
| SCHEMBL7732052 | 0.81 | RAB9A (0.43) | RAB9ANPC1MAPTSMN1; SMN2NFKB1 | |
| Trifluoroacetic Acid SCHEMBL7727095 | 0.80 | SCN9A (0.54) | RAB9ANPC1MAPTSMN1; SMN2NFKB1 | |
| SCHEMBL7731720 | 0.79 | TRPV1 (0.41) | RAB9ANPC1MAPTSMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |