Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.67 |
| ▸ | HTR2B | P41595 | 7/20 | 0.63 |
| ▸ | HTR2A | P28223 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347966 | 1.00 | HTR2C (0.67) | HTR2CHTR2BHTR2A | |
| SCHEMBL4348100 | 1.00 | HTR2C (0.67) | HTR2CHTR2BHTR2A | |
| SCHEMBL20698201 | 0.90 | HTR2C (0.72) | HTR2CHTR2BHTR2A | |
| SCHEMBL7229772 | 0.81 | HTR2C (0.94) | HTR2CHTR2BHTR2A | |
| SCHEMBL4344616 | 0.81 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL16168362 | 0.81 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL4354419 | 0.81 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL20698202 | 0.81 | HTR2C (0.94) | HTR2CHTR2BHTR2A | |
| SCHEMBL29434863 | 0.81 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL4352287 | 0.81 | HTR2C (1.00) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777407-B2 | 7BH-CYCLOPENTA(B)(1,4)DIAZEPINO(6, 7, 1-HI)INDOLE OR A SALT, USEFUL FOR TREATMENT OF SCHIZOPHRENIA, OBSESSIVE COMPULSIVE DISORDER, DEPRESSION, ANXIETY, PANIC DISORDER, OBESITY OR EPILEPSY | WYETH | 2004-08-17 | — | — | US | disclosed |
| US-6777407-B2 | 7BH-CYCLOPENTA(B)(1,4)DIAZEPINO(6, 7, 1-HI)INDOLE OR A SALT, USEFUL FOR TREATMENT OF SCHIZOPHRENIA, OBSESSIVE COMPULSIVE DISORDER, DEPRESSION, ANXIETY, PANIC DISORDER, OBESITY OR EPILEPSY | WYETH | 2004-08-17 | — | — | US | disclosed |