Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CCKBR | P32239 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735981 | 1.00 | LMNA (0.59) | LMNACCKBRHTTSMN1; SMN2GAA | |
| SCHEMBL6154117 | 0.80 | LMNA (0.55) | LMNACCKBRHTTSMN1; SMN2GAA | |
| SCHEMBL633303 | 0.80 | LMNA (0.55) | LMNACCKBRHTTSMN1; SMN2GAA | |
| SCHEMBL633304 | 0.80 | LMNA (0.55) | LMNACCKBRHTTSMN1; SMN2GAA | |
| SCHEMBL16823973 | 0.78 | NPC1 (0.48) | CCKBRSMN1; SMN2ALDH1A1 | |
| SCHEMBL632994 | 0.77 | LMNA (0.55) | LMNACCKBRHTTSMN1; SMN2GAA | |
| SCHEMBL18009235 | 0.77 | LMNA (0.64) | LMNAALDH1A1USP2HPGDHSD17B10 | |
| SCHEMBL1502329 | 0.77 | CYP1A2 (0.52) | LMNACCKBRHTTSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL2826715 | 0.76 | LMNA (0.54) | LMNACCKBRHTTSMN1; SMN2GAA | |
| SCHEMBL1107544 | 0.75 | LMNA (0.55) | LMNAGAANAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403804-B1 | ALLOWING HYDRAZINE TO REACT ON OPTICALLY ACTIVE ACID ESTER HAVING HYDROXYL GROUP AT 3-POSITION TO GIVE OPTICALLY ACTIVE HYDRAZIDE HAVING HYDROXYL GROUP AT 3-POSITION, SUBJECTING OPTICALLY ACTIVE HYDRAZIDE TO CURTIUS REARRANGEMENT | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1008590-A1 | Process for preparing optically active oxazolidinone derivative | Takasago International Corporation (JP) | 2000-06-14 | — | — | EP | disclosed |