Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 20/20 | 0.53 |
| ▸ | RXRG | P48443 | 18/20 | 0.53 |
| ▸ | RARG | P13631 | 8/20 | 0.53 |
| ▸ | RARB | P10826 | 7/20 | 0.53 |
| ▸ | RARA | P10276 | 5/20 | 0.53 |
| ▸ | RXRB | P28702 | 15/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732981 | 0.86 | RXRA (0.63) | RXRARXRGRARGRARBRARA | |
| SCHEMBL7732977 | 0.86 | RXRA (0.63) | RXRARXRGRARGRARBRARA | |
| SCHEMBL7731133 | 0.83 | RXRA (0.55) | RXRARXRGRARGRARBRARA | |
| SCHEMBL7731135 | 0.83 | RXRA (0.55) | RXRARXRGRARGRARBRARA | |
| SCHEMBL6908851 | 0.80 | RXRA (0.54) | RXRARXRGRARGRARBRARA | |
| SCHEMBL8588546 | 0.78 | RXRA (0.77) | RXRARXRGRARGRARBRARA | |
| SCHEMBL8588550 | 0.78 | RXRA (0.77) | RXRARXRGRARGRARBRARA | |
| SCHEMBL8588549 | 0.78 | RXRA (0.77) | RXRARXRGRARGRARBRARA | |
| SCHEMBL7732336 | 0.77 | RXRA (0.45) | RXRARXRGRARGRARBRARA | |
| SCHEMBL7732340 | 0.77 | RXRA (0.45) | RXRARXRGRARGRARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403638-B1 | COMPOUND FOR USE IN TREATING SKIN DISEASES AND DISORDERS, AND FOR TREATING HYPERVITAMINOSIS A SYNDROME | ALLERGAN SALES, INC. | 2002-06-11 | — | — | US | disclosed |