SCHEMBL7736055

SCHEMBL7736055

C=CCN(CC=C)NC(=O)C=C

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
TSHR P16473 2/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LMNA P02545 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TGM2 P21980 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6694454 0.80 ALDH1A1 (0.39) ALDH1A1TSHRLMNAALOX15HSD17B10
SCHEMBL169910 0.78 ALDH1A1 (0.38) ALDH1A1TSHRLMNAALOX15HSD17B10
SCHEMBL9750201 0.76 ALDH1A1 (0.37) ALDH1A1
SCHEMBL3263644 0.76 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL4352238 0.76 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2
SCHEMBL27129866 0.76 TSHR (0.42) ALDH1A1TSHRMAPK1TDP1ZDHHC20
Hydrochloric Acid SCHEMBL9820028 0.74 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2
SCHEMBL588261 0.74 TSHR (0.41) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL5606415 0.73 ALDH1A1 (0.36) ALDH1A1TSHRSMN1; SMN2
SCHEMBL17049179 0.73 ALDH1A1 (0.35) ALDH1A1TSHRMAPK1TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6403537-B1 CATIONIC COPOLYMER OF ACRYLAMIDE MONOMERS AND QUATERNARY SALTS OF N,N-DIALKYLAMINOACRYLAMIDE, A BRIDGING AGENT TO BRIDGE THE PORES IN THE FORMATION; OPTIONALLY 2-AMINO-2-METHYLPROPANE SULFONIC ACID BAKER HUGHES INCORPORATED 2002-06-11 US claimed
WO-2000027944-B1 DRILLING FLUID SYSTEMS WITH IMPROVED FLUID LOSS PROPERTIES BAKER HUGHES INC (US) 2000-08-10 WO claimed
WO-2000027944-A1 DRILLING FLUID SYSTEMS WITH IMPROVED FLUID LOSS PROPERTIES BAKER HUGHES INCORPORATED (US) 2000-05-18 WO claimed
US-6403537-B1 CATIONIC COPOLYMER OF ACRYLAMIDE MONOMERS AND QUATERNARY SALTS OF N,N-DIALKYLAMINOACRYLAMIDE, A BRIDGING AGENT TO BRIDGE THE PORES IN THE FORMATION; OPTIONALLY 2-AMINO-2-METHYLPROPANE SULFONIC ACID BAKER HUGHES INCORPORATED 2002-06-11 US disclosed