Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837796 | 0.88 | PTPN1 (0.46) | PTPN1PTPN2ALDH1A1MEN1KMT2A | |
| SCHEMBL5846085 | 0.86 | BCHE (0.41) | BCHEACHEMAPTTP53FLT3 | |
| SCHEMBL5846091 | 0.86 | BCHE (0.41) | BCHEACHEMAPTTP53FLT3 | |
| SCHEMBL7524893 | 0.83 | PTPN1 (0.45) | PTPN1PTPN2BCHEACHEMAPT | |
| SCHEMBL5837772 | 0.82 | PTPN1 (0.47) | PTPN1PTPN2MAPTKMT2AL3MBTL1 | |
| SCHEMBL5837693 | 0.81 | KMT2A (0.46) | PTPN1PTPN2MAPTTP53ALDH1A1 | |
| SCHEMBL5837651 | 0.80 | DRD4 (0.46) | PTPN1PTPN2MAPTALDH1A1HPGD | |
| SCHEMBL5838423 | 0.79 | MEN1 (0.44) | PTPN1PTPN2ACHETP53MEN1 | |
| SCHEMBL5837592 | 0.79 | PTPN1 (0.50) | PTPN1PTPN2MAPTMEN1KMT2A | |
| SCHEMBL5837558 | 0.78 | PTPN1 (0.42) | PTPN1PTPN2ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410556-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2002-06-25 | — | — | US | claimed |