Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7742008 | 0.64 | DPP4 (0.39) | — | |
| SCHEMBL13394532 | 0.62 | HTR1A (0.40) | — | |
| SCHEMBL25609418 | 0.61 | GRM5 (0.33) | — | |
| SCHEMBL27438351 | 0.61 | GRM5 (0.33) | — | |
| SCHEMBL8890628 | 0.59 | — | — | |
| SCHEMBL9145960 | 0.58 | — | — | |
| SCHEMBL10131713 | 0.56 | PIK3CD (0.32) | — | |
| SCHEMBL11829608 | 0.54 | — | — | |
| SCHEMBL18175949 | 0.52 | SUCNR1 (0.47) | — | |
| SCHEMBL3509202 | 0.51 | TSHR (0.40) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417197-B1 | PRODRUGS FORMED WITH ESTERIFICATION AND ACIDIFICATION | GRUENENTHAL GMBH (DE) | 2002-07-09 | — | — | US | disclosed |