Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 7/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6365679 | 0.94 | POLB (0.45) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL6932273 | 0.90 | POLB (0.44) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL7726485 | 0.90 | POLB (0.42) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL12404747 | 0.89 | POLB (0.49) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL6365808 | 0.86 | P2RY6 (0.47) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL13672352 | 0.86 | P2RY6 (0.47) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL13151571 | 0.86 | P2RY6 (0.47) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL6362501 | 0.83 | POLB (0.39) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL5525210 | 0.83 | POLB (0.36) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL5531861 | 0.81 | P2RY6 (0.40) | POLBABL1RIN1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476205-B1 | 2′ Modified oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2002-11-05 | — | — | US | disclosed |