SCHEMBL7736346

SCHEMBL7736346

CCCCCOc1ccc(-c2cc[c]cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 5/20 0.58
CYP3A4 P08684 4/20 0.58
RARB P10826 3/20 0.57
NR5A1 Q13285 1/20 0.55
LTA4H P09960 2/20 0.53
CYP19A1 P11511 4/20 0.53
CYP2C9 P11712 4/20 0.53
CYP2C19 P33261 4/20 0.53
CYP1A2 P05177 3/20 0.53
KDM4E B2RXH2 3/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
HTT P42858 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TP53 P04637 1/20 0.49
TSHR P16473 1/20 0.49
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7962685 1.00 CYP2D6 (0.58) CYP2D6CYP3A4RARBNR5A1LTA4H
SCHEMBL2221791 0.98 RARB (0.59) CYP2D6CYP3A4RARBNR5A1LTA4H
SCHEMBL8747689 0.98 RARB (0.59) CYP2D6CYP3A4RARBNR5A1LTA4H
SCHEMBL7723569 0.98 RARB (0.59) CYP2D6CYP3A4RARBNR5A1LTA4H
SCHEMBL7731763 0.98 RARB (0.59) CYP2D6CYP3A4RARBNR5A1LTA4H
SCHEMBL2877843 0.98 RARB (0.59) CYP2D6CYP3A4RARBNR5A1LTA4H
SCHEMBL28371462 0.98 RARB (0.59) CYP2D6CYP3A4RARBNR5A1LTA4H
SCHEMBL28068983 0.98 RARB (0.59) CYP2D6CYP3A4RARBNR5A1LTA4H
SCHEMBL3090319 0.96 CYP2D6 (0.61) CYP2D6CYP3A4RARBLTA4HCYP19A1
SCHEMBL10618259 0.91 RARB (0.57) CYP2D6CYP3A4RARBNR5A1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0929508-B1 LIQUID CRYSTALLINE (E,E)-BUTADIENE COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS QINETIQ LTD (GB) 2002-03-20 EP disclosed
US-6333082-B1 USEFUL IN SUPER TWISTED NEMATIC LIQUID CRYSTAL DISPLAYS QINETIQ LTD (GB) 2001-12-25 US disclosed
EP-0929508-A1 LIQUID CRYSTALLINE ($i(E,E))-BUTADIENE COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS THE SECRETARY OF STATE FOR DEFENCE (GB) 1999-07-21 EP disclosed
WO-1998013325-A1 LIQUID CRYSTALLINE (E,E)-BUTADIENE COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS THE SECRETARY OF STATE FOR DEFENCE (GB) 1998-04-02 WO disclosed
EP-0120463-B1 ANTHRAQUINONE DYES AND LIQUID CRYSTAL COMPOSITIONS INCLUDING THE SAME HITACHI, LTD. (JP) 1991-11-06 EP disclosed
EP-0120717-B1 ANTHRAQUINONE DYES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE DYES MITSUBISHI KASEI CORPORATION (JP) 1988-12-07 EP disclosed
US-4610804-A Anthraquinone dyes and liquid crystal compositions including the same HITACHI, LTD. (JP) 1986-09-09 US disclosed
US-4528113-A Anthraquinone dye and liquid crystal composition containing the dye MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1985-07-09 US disclosed
US-4507221-A Anthraquinone dye and liquid crystal composition containing the same MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1985-03-26 US disclosed
EP-0120717-A2 Anthraquinone dyes and liquid crystal compositions containing the dyes MITSUBISHI KASEI CORPORATION (JP) 1984-10-03 EP disclosed
EP-0120463-A2 Anthraquinone dyes and liquid crystal compositions including the same HITACHI, LTD. (JP) 1984-10-03 EP disclosed
EP-0098736-A2 Anthraquinone dyes and liquid crystal compositions containing the dyes MITSUBISHI KASEI CORPORATION (JP) 1984-01-18 EP disclosed