Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.59 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2221791 | 1.00 | RARB (0.59) | RARBNR5A1CYP3A4CYP2D6KDM4E | |
| SCHEMBL28371462 | 1.00 | RARB (0.59) | RARBNR5A1CYP3A4CYP2D6KDM4E | |
| SCHEMBL2877843 | 1.00 | RARB (0.59) | RARBNR5A1CYP3A4CYP2D6KDM4E | |
| SCHEMBL7723569 | 1.00 | RARB (0.59) | RARBNR5A1CYP3A4CYP2D6KDM4E | |
| SCHEMBL7731763 | 1.00 | RARB (0.59) | RARBNR5A1CYP3A4CYP2D6KDM4E | |
| SCHEMBL28068983 | 1.00 | RARB (0.59) | RARBNR5A1CYP3A4CYP2D6KDM4E | |
| SCHEMBL7736346 | 0.98 | CYP2D6 (0.58) | RARBNR5A1CYP3A4CYP2D6KDM4E | |
| SCHEMBL7962685 | 0.98 | CYP2D6 (0.58) | RARBNR5A1CYP3A4CYP2D6KDM4E | |
| SCHEMBL3090319 | 0.94 | CYP2D6 (0.61) | RARBCYP3A4CYP2D6KDM4ELTA4H | |
| SCHEMBL10618259 | 0.92 | RARB (0.57) | RARBNR5A1CYP3A4CYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520281-B1 | Optical element for generating short wave laser light | HOFFMANN LA ROCHE (CH) | 1997-03-12 | — | — | EP | disclosed |
| EP-0520281-A2 | Optical element for generating short wave laser light | F. HOFFMANN-LA ROCHE AG (CH) | 1992-12-30 | — | — | EP | disclosed |