Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737153 | 0.86 | PTGIR (0.47) | PPARGHRH3ALDH1A1PRMT5WDR77 | |
| SCHEMBL7730180 | 0.83 | HRH3 (0.40) | PPARDPPARGPKMHRH3SMN1; SMN2 | |
| SCHEMBL7736514 | 0.82 | PTGIR (0.46) | HRH3ALDH1A1PRMT5WDR77PTGIR | |
| SCHEMBL7737711 | 0.81 | HRH3 (0.41) | PPARDPPARGPKMHRH3SMN1; SMN2 | |
| SCHEMBL7730171 | 0.81 | PTGIR (0.48) | PPARDPPARGPKMHRH3SMN1; SMN2 | |
| SCHEMBL7730032 | 0.80 | PTGIR (0.58) | SMN1; SMN2CYP2C19ALDH1A1MAPTNPC1 | |
| SCHEMBL7737079 | 0.80 | PTGIR (0.47) | PPARDPPARGPKMHRH3ALDH1A1 | |
| SCHEMBL7736464 | 0.80 | PTGIR (0.46) | PPARDHRH3HDAC1HDAC6PTGIR | |
| SCHEMBL7737082 | 0.79 | HRH3 (0.46) | HRH3SMN1; SMN2MEN1KMT2AHDAC1 | |
| SCHEMBL7737206 | 0.79 | PTGIR (0.48) | PPARGHRH3ALDH1A1PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |