SCHEMBL7736622

SCHEMBL7736622

CCCCOC(=O)c1ccc(N)cc1C(=O)OCc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.76
TSHR P16473 7/20 0.76
TDP1 Q9NUW8 5/20 0.76
CYP3A4 P08684 4/20 0.76
L3MBTL1 Q9Y468 4/20 0.76
MAPK1 P28482 3/20 0.76
HSD17B10 Q99714 3/20 0.56
TP53 P04637 2/20 0.54
LMNA P02545 2/20 0.52
CYP1A2 P05177 2/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
PDE4D Q08499 1/20 0.51
KDM4E B2RXH2 2/20 0.50
POLB P06746 1/20 0.50
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
MAPT P10636 1/20 0.46
CYP2D6 P10635 1/20 0.46
SCN1A P35498 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7723903 1.00 ALDH1A1 (0.76) ALDH1A1TSHRTDP1CYP3A4L3MBTL1
SCHEMBL28103489 0.99 ALDH1A1 (0.78) ALDH1A1TSHRTDP1CYP3A4L3MBTL1
SCHEMBL7734044 0.88 TSHR (0.65) ALDH1A1TSHRTDP1CYP3A4L3MBTL1
SCHEMBL23812434 0.88 ALDH1A1 (0.63) ALDH1A1TSHRTDP1CYP3A4L3MBTL1
SCHEMBL29507350 0.87 TSHR (1.00) ALDH1A1TSHRTDP1CYP3A4L3MBTL1
SCHEMBL49678 0.87 TSHR (1.00) ALDH1A1TSHRTDP1CYP3A4L3MBTL1
SCHEMBL29507351 0.87 TSHR (1.00) ALDH1A1TSHRTDP1CYP3A4L3MBTL1
Dibutyl Phthalate SCHEMBL10408632 0.87 TSHR (1.00) ALDH1A1TSHRTDP1CYP3A4L3MBTL1
SCHEMBL6278559 0.87 TSHR (1.00) ALDH1A1TSHRTDP1CYP3A4L3MBTL1
Dibutyl Phthalate SCHEMBL28606944 0.87 TSHR (1.00) ALDH1A1TSHRTDP1CYP3A4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106496824-A A kind of coffee package aluminizer 无锡三帝特种高分子材料有限公司 2017-03-15 CN claimed
CN-104370761-A Benzyl butyl phthalate hapten derivative, preparation method of benzyl butyl phthalate hapten derivative and detection method of benzyl butyl phthalate UNIV ANHUI NORMAL 2015-02-25 CN claimed
CN-106496824-A A kind of coffee package aluminizer 无锡三帝特种高分子材料有限公司 2017-03-15 CN disclosed
CN-104370761-B A kind of butyl benzyl phthalate hapten derivant and preparation method, the detection method of butyl benzyl phthalate 安徽师范大学 2016-09-14 CN disclosed
CN-104370761-A Benzyl butyl phthalate hapten derivative, preparation method of benzyl butyl phthalate hapten derivative and detection method of benzyl butyl phthalate UNIV ANHUI NORMAL 2015-02-25 CN disclosed
US-6399318-B1 ANTIGEN WHICH IS CONJUGATE OF CARRIER PROTEIN AND PHTHALIC ACID ESTER OF DEFINED STRUCTURE; FOR DETECTION AND MEASUREMENT OF PLASTICIZERS IN ENVIRONMENT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2002-06-04 US disclosed