Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | STAT3 | P40763 | 1/20 | 0.62 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.62 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.56 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.50 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724422 | 0.85 | MAPT (0.62) | MEN1KMT2ALMNAGAAKCNJ5 | |
| SCHEMBL7734705 | 0.82 | MAPK1 (0.74) | MEN1KMT2ALMNAGAASTAT3 | |
| SCHEMBL5144511 | 0.80 | POLB (0.86) | MEN1KMT2ALMNAGAASTAT3 | |
| SCHEMBL17479244 | 0.78 | KMT2A (0.54) | MEN1KMT2ALMNAGAASTAT3 | |
| SCHEMBL30612630 | 0.77 | POLB (0.75) | MEN1KMT2ALMNAGAASTAT3 | |
| SCHEMBL247350 | 0.77 | POLB (0.75) | MEN1KMT2ALMNAGAASTAT3 | |
| SCHEMBL7724894 | 0.76 | KCNJ5 (0.51) | MEN1KMT2ALMNAGAASTAT3 | |
| SCHEMBL28844870 | 0.76 | BACE1 (0.56) | MEN1KMT2ALMNAGAAKCNJ5 | |
| SCHEMBL29733128 | 0.76 | BACE1 (0.56) | MEN1KMT2ALMNAGAAKCNJ5 | |
| SCHEMBL10634763 | 0.75 | POLB (0.73) | MEN1KMT2ALMNAGAASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |