Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.60 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.56 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.56 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.56 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.54 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7736629 | 0.85 | MEN1 (0.70) | KCNQ2KCNJ5KCNJ3ERCC1ERCC4 | |
| SCHEMBL8788960 | 0.83 | MAPT (0.55) | MAPTKCNQ2PARP14KCNJ5KCNJ3 | |
| SCHEMBL28600470 | 0.81 | KMT2A (0.66) | MAPTKCNQ2KCNJ5KCNJ3KMT2A | |
| SCHEMBL8632192 | 0.81 | KCNQ2 (0.58) | KCNQ2PARP14KCNJ5KCNJ3KMT2A | |
| SCHEMBL8636686 | 0.81 | MAPK8 (0.67) | KCNQ2PARP14KCNJ5KCNJ3KMT2A | |
| SCHEMBL6579874 | 0.79 | KDM4E (0.52) | MAPTKCNQ2PARP14KCNJ5KCNJ3 | |
| SCHEMBL11285417 | 0.78 | KMT2A (0.70) | MAPTKMT2AGAAALDH1A1HPGD | |
| SCHEMBL28618234 | 0.78 | ALDH1A1 (0.54) | MAPTKCNQ2PARP14KCNJ5KCNJ3 | |
| SCHEMBL28600464 | 0.78 | MAPK10 (0.68) | KCNQ2KMT2AGAAALDH1A1TSHR | |
| SCHEMBL28736029 | 0.77 | TTR (0.57) | KCNJ5KCNJ3ERCC1ERCC4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |