Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496505 | 0.92 | MAOB (0.43) | MAOBFFAR1SPHK2SPHK1ADAMTS4 | |
| SCHEMBL7741762 | 0.92 | HDAC1 (0.37) | MAOBPPARGADAMTS4MMP13MMP2 | |
| SCHEMBL7742973 | 0.91 | NPC1 (0.39) | MAOBFFAR1PPARAHIF1A | |
| SCHEMBL7497710 | 0.86 | MAOB (0.41) | MAOBFFAR1SPHK2SPHK1ADAMTS4 | |
| SCHEMBL7493123 | 0.86 | MAOB (0.41) | MAOBSPHK2SPHK1ADAMTS4MMP13 | |
| SCHEMBL8441800 | 0.86 | MAPK14 (0.37) | HIF1A | |
| SCHEMBL7499092 | 0.85 | MAOB (0.39) | MAOBFFAR1PPARGSLC6A5PPARA | |
| SCHEMBL7736851 | 0.84 | MAOB (0.41) | MAOBFFAR1SPHK2SPHK1ADAMTS4 | |
| SCHEMBL7743206 | 0.84 | HDAC1 (0.35) | MAOBFFAR1PPARAADAMTS4MMP13 | |
| SCHEMBL7498420 | 0.83 | SMN1; SMN2 (0.36) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420423-B1 | PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |
| US-5985921-A | OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS | NOVARTIS CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |