Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741762 | 0.93 | HDAC1 (0.37) | NPC1RAB9ASMN1; SMN2TDP1MAOB | |
| SCHEMBL7498420 | 0.91 | SMN1; SMN2 (0.36) | NPC1RAB9ASMN1; SMN2TDP1KDM4E | |
| SCHEMBL7736860 | 0.91 | MAOB (0.39) | HIF1AMAOBFFAR1PPARA | |
| SCHEMBL8030454 | 0.90 | L3MBTL1 (0.37) | NPC1RAB9AHIF1ASMN1; SMN2TDP1 | |
| SCHEMBL7496505 | 0.86 | MAOB (0.43) | HIF1AL3MBTL1MAOBNR4A2FFAR1 | |
| SCHEMBL8723874 | 0.85 | KDM4E (0.32) | RAB9ASMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL7743206 | 0.85 | HDAC1 (0.35) | NPC1RAB9AMAOAMAOBNR4A2 | |
| SCHEMBL7499630 | 0.84 | MAOB (0.31) | MAOAMAOB | |
| SCHEMBL7495603 | 0.84 | ALDH1A1 (0.34) | FFAR1ALDH1A1 | |
| SCHEMBL7744876 | 0.81 | MAPT (0.35) | NPC1RAB9ASMN1; SMN2TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420423-B1 | PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |
| US-5985921-A | OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS | NOVARTIS CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |