Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737484 | 0.97 | POLB (0.33) | TLR8POLBAPEX1HTTTDP1 | |
| SCHEMBL7736905 | 0.94 | NPC1 (0.32) | NPC1RAB9ARXFP1TP53MAPT | |
| SCHEMBL22572592 | 0.92 | TSHR (0.35) | TLR8TDP1RAB9AMAPTTSHR | |
| SCHEMBL7026729 | 0.91 | NPC1 (0.32) | NPC1RAB9A | |
| SCHEMBL28908795 | 0.91 | TLR8 (0.31) | TLR8 | |
| SCHEMBL7739360 | 0.90 | TNKS2 (0.32) | TNKS2POLBAPEX1HTTTDP1 | |
| SCHEMBL7729403 | 0.89 | NPC1 (0.36) | TNKS2POLBAPEX1HTTTDP1 | |
| SCHEMBL1004781 | 0.88 | TNKS2 (0.43) | TLR8TNKS2POLB | |
| SCHEMBL7030783 | 0.88 | NPC1 (0.42) | POLBTDP1NPC1RAB9ATP53 | |
| SCHEMBL227535 | 0.87 | GAA (0.33) | TLR8TNKS2POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414100-B1 | COMPOUND HAVING EXTREMELY LOW VAPOR PRESSURE AND HIGH DECOMPOSITION TEMPERATURE; CROSSLINKING AGENT FOR WEATHER RESISTANT POLYMERS | OTSUKA CHEMICAL CO., LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1055669-A1 | BISBENZOTRIAZOLYLPHENOL COMPOUNDS, ULTRAVIOLET ABSORBER, ULTRAVIOLET-ABSORBING POLYMER, AND RESIN COMPOSITION AND COATING MATERIAL BOTH CONTAINING THESE | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 2000-11-29 | — | — | EP | disclosed |