Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29370220 | 1.00 | GAA (0.33) | GAATLR8TNKS2POLBAPEX1 | |
| SCHEMBL29384523 | 0.95 | GAA (0.31) | GAAHTTMAOAMAOB | |
| SCHEMBL93350 | 0.95 | GAA (0.31) | GAAHTTMAOAMAOB | |
| SCHEMBL14213069 | 0.90 | NPC1 (0.34) | GAATNKS2POLBAPEX1HTT | |
| SCHEMBL25282759 | 0.90 | POLB (0.32) | POLBAPEX1HTTTDP1 | |
| SCHEMBL3880166 | 0.90 | GAA (0.36) | GAATNKS2POLBAPEX1HTT | |
| SCHEMBL29716387 | 0.90 | GAA (0.36) | GAATNKS2POLBAPEX1HTT | |
| SCHEMBL12128112 | 0.89 | GAA (0.33) | GAATNKS2POLBAPEX1HTT | |
| SCHEMBL1973788 | 0.89 | RXFP1 (0.33) | GAAHTTKDM4EALDH1A1 | |
| SCHEMBL12231778 | 0.89 | TNKS2 (0.34) | GAATNKS2POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1604 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260110920-A1 | MATERIALS AND METHODS FOR LIGHT ADJUSTABLE OPHTHALMIC DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2026-04-23 | — | — | US | claimed |
| US-12595368-B2 | UV/HEVL-filtering contact lenses | ALCON INC. (CH) | 2026-04-07 | — | — | US | claimed |
| US-20260028439-A1 | COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2026-01-29 | — | — | US | claimed |
| US-12460032-B2 | Compositions with high refractive index and Abbe number | Johnson & Johnson Surgical Vision, Inc. (US) | 2025-11-04 | — | — | US | claimed |
| EP-4626495-A1 | OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF | Johnson & Johnson Surgical Vision, Inc. (US) | 2025-10-08 | — | — | EP | claimed |
| US-20250223392-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC (CH) | 2025-07-10 | — | — | US | claimed |
| US-12286501-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2025-04-29 | — | — | US | claimed |
| US-20240254269-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2024-08-01 | — | — | US | claimed |
| US-20240218102-A1 | COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER | Johnson & Johnson Surgical Vision, Inc. | 2024-07-04 | — | — | US | claimed |
| US-20240209129-A1 | OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF | Johnson & Johnson Surgical Vision, Inc. | 2024-06-27 | — | — | US | claimed |
| US-20020042483-A1 | High refractive index hydrogel compositions for ophthalmic implants | VANDERBILT DAVID P (US) | 2002-04-11 | — | — | US | claimed |
| US-20020037984-A1 | High refractive index hydrogel compositions for ophthalmic implants | VANDERBILT DAVID P (US) | 2002-03-28 | — | — | US | claimed |
| US-6329485-B1 | FOR INTRAOCULAR LENSES | BAUSCH & LOMB INCORPORATED | 2001-12-11 | — | — | US | claimed |
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |
| EP-0415765-B1 | Method of preparing composite polymer rods useful for preparing single-piece intraocular lenses with colored haptics | IOLAB CORP (US) | 1994-05-11 | — | — | EP | claimed |
| US-5089180-A | METHOD OF PREPARING COMPOSITE SINGLE-PIECE INTRAOCULAR LENSES WITH COLORED HAPTICS | IOLAB CORPORATION (US) | 1992-02-18 | — | — | US | claimed |
| EP-0415765-A2 | Method of preparing composite polymer rods useful for preparing single-piece intraocular lenses with colored haptics | IOLAB CORPORATION (US) | 1991-03-06 | — | — | EP | claimed |
| EP-0131468-B1 | ULTRAVIOLET ABSORBING POLYMERS COMPRISING 2-HYDROXY-5-ACRYLYLOXALKYLPHENYL-2H-BENZOTRIAZOLES | IOLAB CORPORATION (US) | 1990-01-17 | — | — | EP | claimed |
| US-4889664-A | MOLDING HYDROPHILIC (METH)ACRYLATE ESTER AND WATER DISPLACABLE BORIC ACID ESTER DILUENT | VISTAKON, INC. (US) | 1989-12-26 | — | — | US | claimed |
| US-4528311-A | Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxyphenyl-2H-benzotriazoles | IOLAB CORPORATION (US) | 1985-07-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260110920-A1 | MATERIALS AND METHODS FOR LIGHT ADJUSTABLE OPHTHALMIC DEVICES | ERCC1, ERCC5, ERCC4 | GAA 4260/4885TLR8 227/4885TNKS2 3269/4885 |
| US-12595368-B2 | UV/HEVL-filtering contact lenses | UACA, HSPA4L, RAD54L | GAA 2663/4885TLR8 3745/4885TNKS2 3903/4885 |
| US-20260028439-A1 | COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER | SMCHD1, MACF1, LAGE3 | GAA 4856/4885TLR8 112/4885TNKS2 2446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.