Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.48 |
| ▸ | PTGIR | P43119 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737376 | 0.95 | TBXA2R (0.48) | TBXA2RPTGIRPPARDDRD2DRD3 | |
| SCHEMBL7730171 | 0.85 | PTGIR (0.48) | TBXA2RPTGIRPPARDPPARAPPARG | |
| SCHEMBL7730044 | 0.85 | PTGIR (0.48) | TBXA2RPTGIRPPARDPPARAPPARG | |
| SCHEMBL7737346 | 0.82 | PTGIR (0.49) | TBXA2RPTGIRDRD2ALDH1A1L3MBTL1 | |
| SCHEMBL7729838 | 0.82 | PTGIR (0.47) | TBXA2RPTGIRPPARDPPARAPPARG | |
| SCHEMBL7737368 | 0.80 | PTGIR (0.46) | TBXA2RPTGIRPPARDPPARGL3MBTL1 | |
| SCHEMBL7737711 | 0.78 | HRH3 (0.41) | TBXA2RPTGIRPPARDPPARAPPARG | |
| SCHEMBL7739681 | 0.75 | PTGIR (0.46) | TBXA2RPTGIRLOXL2 | |
| SCHEMBL7730180 | 0.74 | HRH3 (0.40) | TBXA2RPTGIRPPARDPPARAPPARG | |
| SCHEMBL7736580 | 0.73 | PTGIR (0.48) | TBXA2RPTGIRALDH1A1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |