Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 7/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737376 | 0.83 | TBXA2R (0.48) | PTGIRTBXA2RALDH1A1DRD2POLB | |
| SCHEMBL7739735 | 0.82 | HTR1A (0.39) | PTGIRTBXA2RALDH1A1MEN1KMT2A | |
| SCHEMBL7730002 | 0.82 | PTGIR (0.55) | PTGIRTBXA2RALDH1A1POLBTSHR | |
| SCHEMBL7737236 | 0.82 | TBXA2R (0.48) | PTGIRTBXA2RALDH1A1DRD2POLB | |
| SCHEMBL7736555 | 0.81 | PTGIR (0.47) | PTGIRTBXA2RALDH1A1DRD2HTR2A | |
| SCHEMBL7737834 | 0.81 | PTGIR (0.43) | PTGIRALDH1A1DRD2HTR2AMCHR1 | |
| SCHEMBL7737686 | 0.79 | ALDH1A1 (0.39) | PTGIRTBXA2RALDH1A1MEN1KMT2A | |
| SCHEMBL7739724 | 0.79 | PTGIR (0.54) | PTGIRTBXA2RKMT2APOLBTSHR | |
| SCHEMBL7737492 | 0.76 | PTGIR (0.51) | PTGIRTBXA2RALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7730063 | 0.74 | PTGIR (0.55) | PTGIRTBXA2RALDH1A1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |