Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.70 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729962 | 0.94 | PTGIR (0.65) | PTGIRCYSLTR2CYSLTR1KDM4EPTGDR2 | |
| SCHEMBL7736584 | 0.93 | PTGIR (0.64) | PTGIRCYSLTR2CYSLTR1KDM4EPTGDR2 | |
| SCHEMBL7736609 | 0.88 | PTGIR (0.61) | PTGIRCYSLTR2CYSLTR1KDM4EPTGDR2 | |
| SCHEMBL7736442 | 0.85 | PTGIR (0.62) | PTGIRCYSLTR2CYSLTR1KDM4EPTGDR2 | |
| SCHEMBL7736507 | 0.84 | PTGIR (0.63) | PTGIRCYSLTR2CYSLTR1KDM4EPTGDR2 | |
| SCHEMBL7729950 | 0.80 | PTGIR (0.58) | PTGIRCYSLTR2CYSLTR1KDM4EPTGDR2 | |
| SCHEMBL7737680 | 0.80 | PTGIR (0.46) | PTGIRKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL7736944 | 0.79 | PTGIR (0.60) | PTGIRCYSLTR2CYSLTR1SLC6A4 | |
| SCHEMBL7730032 | 0.79 | PTGIR (0.58) | PTGIRCYSLTR2CYSLTR1KDM4EPTGDR2 | |
| SCHEMBL7737347 | 0.78 | PTGIR (0.57) | PTGIRCYSLTR2CYSLTR1KDM4EPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |