Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088204 | 0.92 | KMT2A (0.49) | KMT2ACYP2D6ATML3MBTL1LMNA | |
| SCHEMBL6813755 | 0.90 | KMT2A (0.53) | KMT2ACYP2D6ATML3MBTL1LMNA | |
| SCHEMBL6702668 | 0.84 | KMT2A (0.47) | KMT2ACYP2D6ATML3MBTL1LTA4H | |
| SCHEMBL6647558 | 0.84 | KMT2A (0.47) | KMT2ACYP2D6ATML3MBTL1LTA4H | |
| SCHEMBL27598805 | 0.84 | KMT2A (0.47) | KMT2ACYP2D6ATML3MBTL1LTA4H | |
| SCHEMBL11027683 | 0.83 | KMT2A (0.41) | KMT2ACYP2D6ATML3MBTL1AOC3 | |
| SCHEMBL28874131 | 0.83 | KMT2A (0.41) | KMT2ACYP2D6ATML3MBTL1LMNA | |
| SCHEMBL24851748 | 0.82 | KMT2A (0.52) | KMT2ACYP2D6ATML3MBTL1AOC3 | |
| SCHEMBL1919826 | 0.81 | CYP2D6 (0.50) | KMT2ACYP2D6ATML3MBTL1AOC3 | |
| SCHEMBL8023362 | 0.81 | KMT2A (0.50) | KMT2ACYP2D6ATML3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835123-A4 | AMINOPEPTIDASE P INHIBITORS AND USES THEREOF | UNIV LOYOLA CHICAGO (US) | 2001-05-16 | — | — | EP | disclosed |
| EP-0835123-A1 | AMINOPEPTIDASE P INHIBITORS AND USES THEREOF | LOYOLA UNIVERSITY OF CHICAGO (US) | 1998-04-15 | — | — | EP | disclosed |
| WO-1996039163-A1 | AMINOPEPTIDASE P INHIBITORS AND USES THEREOF | LOYOLA UNIVERSITY OF CHICAGO (US) | 1996-12-12 | — | — | WO | disclosed |