Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737367 | 0.90 | KMT2A (0.45) | KMT2ALTA4HCTSSCTSKCYP3A4 | |
| SCHEMBL7088204 | 0.85 | KMT2A (0.49) | KMT2ACTSSCTSKCYP2D6MAPK1 | |
| SCHEMBL28874131 | 0.80 | KMT2A (0.41) | KMT2ALTA4HCTSSCTSKCYP3A4 | |
| SCHEMBL11027683 | 0.80 | KMT2A (0.41) | KMT2ALTA4HCTSSCTSKCYP1A2 | |
| SCHEMBL24851748 | 0.79 | KMT2A (0.52) | KMT2ACTSSCTSKCYP1A2CYP2D6 | |
| SCHEMBL6647558 | 0.78 | KMT2A (0.47) | KMT2ALTA4HCTSSCTSKCYP1A2 | |
| SCHEMBL27598805 | 0.78 | KMT2A (0.47) | KMT2ALTA4HCTSSCTSKCYP1A2 | |
| SCHEMBL6702668 | 0.78 | KMT2A (0.47) | KMT2ALTA4HCTSSCTSKCYP1A2 | |
| SCHEMBL8023362 | 0.77 | KMT2A (0.50) | KMT2ACTSSCTSKCYP2D6MAPK1 | |
| SCHEMBL6896070 | 0.77 | DPP4 (0.43) | KMT2ACTSSCTSKCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052257-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE THREO-3-AMINO-1,2-EPOXY COMPOUNDS | NIPPON KAYAKU KK (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6452026-B1 | REACTING THREO-3-AMINO-1,2-DIOL COMPOUND WITH SULFONYLATING AGENT AND EPOXIDATION TO FORM 3-AMINO-1,2-EPOXY COMPOUND | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-09-17 | — | — | US | disclosed |
| US-20020058825-A1 | Process for producing optically active threo-3-amino-1,2-epoxy compounds | SAGAWA YUKIHIRO (JP) | 2002-05-16 | — | — | US | disclosed |
| US-6376685-B1 | SULFONYLATION; CYCLIZATION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1052257-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE THREO-3-AMINO-1,2-EPOXY COMPOUNDS | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058825-A1 | Process for producing optically active threo-3-amino-1,2-epoxy compounds | DAO, DHPS, ALKBH3 | KMT2A 1399/4885LTA4H 971/4885CTSS 1328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.