Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850301 | 0.83 | KDM4E (0.41) | F2PRSS1KDM4EALDH1A1 | |
| SCHEMBL6846378 | 0.83 | KDM4E (0.44) | F2PRSS1KDM4EALDH1A1 | |
| SCHEMBL7737238 | 0.79 | F2 (0.53) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7737891 | 0.78 | F2 (0.54) | F2PRSS1KDM4EALDH1A1LMNA | |
| SCHEMBL6849324 | 0.78 | MASP2 (0.38) | F2PRSS1KDM4EALDH1A1 | |
| SCHEMBL6850182 | 0.76 | KDM4E (0.42) | F2KDM4EALDH1A1 | |
| SCHEMBL8362741 | 0.66 | F2 (0.47) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8362786 | 0.64 | F2 (0.52) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5474673 | 0.64 | F2 (0.61) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6846360 | 0.62 | F2 (0.58) | F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777431-B2 | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2004-08-17 | — | — | US | disclosed |
| US-6777431-B2 | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2004-08-17 | — | — | US | disclosed |