Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | SELE | P16581 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15349912 | 0.86 | KDM4C (0.53) | KDM4CICAM1SELEL3MBTL1NPC1 | |
| SCHEMBL1548491 | 0.83 | KDM4C (0.43) | KDM4CICAM1SELEL3MBTL1NPC1 | |
| SCHEMBL26667763 | 0.83 | L3MBTL1 (0.46) | KDM4CICAM1SELEL3MBTL1NPC1 | |
| SCHEMBL4079719 | 0.81 | ICAM1 (0.42) | KDM4CICAM1SELEL3MBTL1NPC1 | |
| SCHEMBL2884836 | 0.81 | ICAM1 (0.42) | KDM4CICAM1SELEL3MBTL1NPC1 | |
| SCHEMBL22070905 | 0.80 | KDM4C (0.43) | KDM4CICAM1SELEL3MBTL1NPC1 | |
| SCHEMBL17288096 | 0.78 | MEN1 (0.51) | KDM4CICAM1SELEL3MBTL1NPC1 | |
| SCHEMBL15919709 | 0.78 | MEN1 (0.57) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL21069390 | 0.78 | KDM4C (0.47) | KDM4CICAM1SELEL3MBTL1NPC1 | |
| SCHEMBL3999018 | 0.78 | ICAM1 (0.42) | KDM4CICAM1SELEL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |