Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4386642 | 0.79 | NR1H2 (0.47) | NR1H2NR1H3 | |
| SCHEMBL7737532 | 0.76 | NR1H2 (0.45) | NR1H2NR1H3 | |
| SCHEMBL8836682 | 0.75 | NR1H2 (0.63) | NR1H2NR1H3 | |
| SCHEMBL7737536 | 0.75 | NR1H2 (0.51) | NR1H2NR1H3 | |
| SCHEMBL7740885 | 0.73 | NR1H2 (0.46) | NR1H2NR1H3 | |
| SCHEMBL7732429 | 0.70 | NR1H2 (0.50) | NR1H2NR1H3 | |
| SCHEMBL4377400 | 0.70 | KDM4E (0.42) | NR1H2NR1H3 | |
| SCHEMBL7732421 | 0.69 | NR1H2 (0.39) | NR1H2NR1H3 | |
| SCHEMBL9797866 | 0.69 | ALDH1A1 (0.42) | KCNJ1 | |
| SCHEMBL10941257 | 0.69 | NR1H2 (0.56) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |