Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17540833 | 0.86 | KDM4E (0.49) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL3886258 | 0.83 | KDM4E (0.50) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL4709421 | 0.81 | KDM4E (0.46) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL18924759 | 0.80 | KDM4E (0.48) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL10480745 | 0.80 | SMN1; SMN2 (0.46) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL27597513 | 0.79 | HPGD (0.43) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL27536014 | 0.78 | KDM4E (0.49) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL4389204 | 0.78 | PPARG (0.47) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL4929594 | 0.76 | KDM4E (0.47) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL8573767 | 0.74 | GAA (0.51) | KDM4ERAB9ANPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414001-B2 | Ether and amide compounds preparation thereof composition containing same and use thereof as antidiadetics | KOTOBUKI PHARMACEUTICAL CO. LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| CN-1315320-A | Ether and amide compounds as medicide for treating glycuresis and preparing process thereof | KOTOBUKI SEIYAKU CO LTD (JP) | 2001-10-03 | — | — | CN | disclosed |
| US-20010008898-A1 | Ether and amide compounds and preparation of thereof as antidiadetics. | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2001-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010008898-A1 | Ether and amide compounds and preparation of thereof as antidiadetics. | SLC5A2, GCG, NCEH1 | KDM4E 2318/4885RAB9A 1873/4885NPC1 721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.