Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.62 |
| ▸ | PPARA | Q07869 | 15/20 | 0.62 |
| ▸ | PPARD | Q03181 | 8/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738146 | 0.88 | PPARG (0.68) | PPARGPPARAPPARD | |
| Trifluoromethanesulfonamide SCHEMBL7737833 | 0.84 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL7738134 | 0.84 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL5563043 | 0.82 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL7730865 | 0.81 | PPARG (0.61) | PPARGPPARAPPARD | |
| SCHEMBL4389208 | 0.80 | PPARG (0.79) | PPARGPPARAPPARD | |
| Methanesulfonamide SCHEMBL7737856 | 0.80 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL7730828 | 0.79 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL9721974 | 0.79 | KDR (0.58) | PPARGPPARA | |
| SCHEMBL3283978 | 0.79 | PPARG (0.77) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414001-B2 | Ether and amide compounds preparation thereof composition containing same and use thereof as antidiadetics | KOTOBUKI PHARMACEUTICAL CO. LTD. (JP) | 2002-07-02 | — | — | US | disclosed |