Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.65 |
| ▸ | PPARA | Q07869 | 17/20 | 0.65 |
| ▸ | PPARD | Q03181 | 9/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methanesulfonamide SCHEMBL7737856 | 0.91 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL4389208 | 0.87 | PPARG (0.79) | PPARGPPARAPPARD | |
| SCHEMBL7737836 | 0.84 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL7736876 | 0.81 | PPARG (0.74) | PPARGPPARAPPARD | |
| SCHEMBL3283978 | 0.81 | PPARG (0.77) | PPARGPPARAPPARD | |
| SCHEMBL14002819 | 0.81 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL5098728 | 0.80 | PPARG (0.76) | PPARGPPARAPPARD | |
| SCHEMBL5110945 | 0.79 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL9537307 | 0.79 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL1122908 | 0.79 | PPARG (0.78) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414001-B2 | Ether and amide compounds preparation thereof composition containing same and use thereof as antidiadetics | KOTOBUKI PHARMACEUTICAL CO. LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| US-20010008898-A1 | Ether and amide compounds and preparation of thereof as antidiadetics. | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2001-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010008898-A1 | Ether and amide compounds and preparation of thereof as antidiadetics. | SLC5A2, GCG, NCEH1 | PPARG 428/4885PPARA 404/4885PPARD 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.