Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.72 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.67 |
| ▸ | PLD2 | O14939 | 4/20 | 0.64 |
| ▸ | PLD1 | Q13393 | 3/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.58 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7736356 | 0.91 | NPY5R (0.73) | NPY5ROPRM1PLD2PLD1OPRK1 | |
| SCHEMBL7735743 | 0.91 | NPY5R (0.73) | NPY5ROPRM1PLD2PLD1OPRK1 | |
| SCHEMBL7735736 | 0.90 | NPY5R (0.72) | NPY5ROPRM1PLD2PLD1OPRK1 | |
| SCHEMBL7734810 | 0.90 | OPRM1 (0.78) | NPY5ROPRM1PLD2PLD1OPRK1 | |
| SCHEMBL7736005 | 0.88 | NPY5R (0.69) | NPY5ROPRM1PLD2PLD1OPRK1 | |
| SCHEMBL8159806 | 0.88 | NPY5R (0.69) | NPY5ROPRM1PLD2PLD1OPRK1 | |
| SCHEMBL8155283 | 0.87 | NPY5R (0.68) | NPY5ROPRM1PLD2PLD1OPRK1 | |
| SCHEMBL7734850 | 0.87 | NPY5R (0.68) | NPY5ROPRM1PLD2PLD1OPRK1 | |
| SCHEMBL7736020 | 0.87 | NPY5R (0.70) | NPY5ROPRM1PLD2PLD1OPRK1 | |
| SCHEMBL7735746 | 0.86 | NPY5R (0.67) | NPY5ROPRM1PLD2PLD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410792-B1 | OBESITY DISEASES | BAYER CORPORATION | 2002-06-25 | — | — | US | claimed |