SCHEMBL7738286

SCHEMBL7738286

[CH2]c1ccc(OC)c(OC)c1[N+](=O)[O-]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
PKM P14618 1/20 0.44
ALDH1A1 P00352 2/20 0.42
MCL1 Q07820 1/20 0.41
TUBB4A P04350 2/20 0.41
TUBB P07437 2/20 0.41
TUBA3C P0DPH7 2/20 0.41
TUBA1B P68363 2/20 0.41
TUBA4A P68366 2/20 0.41
TUBB4B P68371 2/20 0.41
TUBB3 Q13509 2/20 0.41
TUBB2A Q13885 2/20 0.41
TUBB8 Q3ZCM7 2/20 0.41
TUBA3E Q6PEY2 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14420116 0.80 TDP1 (0.49) TDP1KDM4EPOLBCTDSP1L3MBTL1
SCHEMBL8136793 0.80 ALDH1A1 (0.52) TDP1KDM4EPOLBCTDSP1L3MBTL1
SCHEMBL622685 0.79 TDP1 (0.57) TDP1KDM4EPOLBCTDSP1L3MBTL1
SCHEMBL8950203 0.79 TDP1 (0.51) TDP1KDM4EPOLBCTDSP1L3MBTL1
SCHEMBL2144902 0.79 TDP1 (0.47) TDP1KDM4EPOLBCTDSP1L3MBTL1
SCHEMBL5964869 0.78 KDM4E (0.44) TDP1KDM4EPOLBCTDSP1L3MBTL1
SCHEMBL2547688 0.78 KMT2A (0.50) TDP1KDM4EPOLBCTDSP1L3MBTL1
SCHEMBL1179747 0.78 TDP1 (0.62) TDP1KDM4EPOLBCTDSP1L3MBTL1
SCHEMBL29396391 0.78 TDP1 (0.62) TDP1KDM4EPOLBCTDSP1L3MBTL1
SCHEMBL3294985 0.78 TDP1 (0.53) TDP1KDM4EPOLBCTDSP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4341269-A1 FUNCTIONAL MOIETIES AND THEIR USES AND SYNTHETIC PREPARATION Olix US, Inc. (US) 2024-03-27 EP disclosed
US-20230357757-A1 SELF-PURIFIED NUCLEIC ACID ENCODED LIBRARIES PETROV, DIMITAR (CH) 2023-11-09 US disclosed
EP-4232578-A1 SELF-PURIFIED NUCLEIC ACID ENCODED LIBRARIES ETH Zurich (CH) 2023-08-30 EP disclosed
WO-2022084486-A1 SELF-PURIFIED NUCLEIC ACID ENCODED LIBRARIES ETH ZURICH (CH) 2022-04-28 WO disclosed
CN-114144487-A Method and article for disposing adhesive onto a substrate 3M创新有限公司 2022-03-04 CN disclosed
CN-107148453-B Photocurable composition 思美定株式会社 2021-08-17 CN disclosed
WO-2021117680-A1 BIOLOGICAL SUBSTANCE IMMOBILIZATION MATERIAL 国立大学法人 東京大学 2021-06-17 WO disclosed
EP-3746490-A1 PHOTOLABILE BETA-DICARBONYL COMPOUNDS 3M Innovative Properties Company (US) 2020-12-09 EP disclosed
US-20200354484-A1 PHOTOLABILE BETA-DICARBONYL COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY 2020-11-12 US disclosed
CN-111683974-A Photolabile beta-dicarbonyl compounds 3M创新有限公司 2020-09-18 CN disclosed
EP-3044204-A1 A PHOTOLABILE LINKER FOR THE SOLID-PHASE SYNTHESIS OF HYDRAZIDES AND PYRANOPYRAZOLES Danmarks Tekniske Universitet (DK) 2016-07-20 EP disclosed
EP-3044204-A1 A PHOTOLABILE LINKER FOR THE SOLID-PHASE SYNTHESIS OF HYDRAZIDES AND PYRANOPYRAZOLES Danmarks Tekniske Universitet (DK) 2016-07-20 EP disclosed
WO-2015036481-A1 A PHOTOLABILE LINKER FOR THE SOLID-PHASE SYNTHESIS OF HYDRAZIDES AND PYRANOPYRAZOLES DANMARKS TEKNISKE UNIVERSITET (DK) 2015-03-19 WO disclosed
WO-2015036481-A1 A PHOTOLABILE LINKER FOR THE SOLID-PHASE SYNTHESIS OF HYDRAZIDES AND PYRANOPYRAZOLES DANMARKS TEKNISKE UNIVERSITET (DK) 2015-03-19 WO disclosed
US-20140273216-A1 Synthetic Lariat RNA for RNA Interference Camegie Mellon University (US) 2014-09-18 US disclosed
EP-1073764-A4 MEMBRANE-PERMEANT PHOSPHOINOSITIDES UNIV CALIFORNIA (US) 2001-11-14 EP disclosed
EP-1073764-A1 MEMBRANE-PERMEANT PHOSPHOINOSITIDES The Regents of the University of California (US) 2001-02-07 EP disclosed
WO-1999055903-A1 MEMBRANE-PERMEANT PHOSPHOINOSITIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1999-11-04 WO disclosed
US-5955453-A Membrane-permeant phosphoinositides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1999-09-21 US disclosed
EP-0821690-A1 NOVEL COMPOUNDS AND METHODS FOR THERAPY Ustav Organicke Chemie A Biochemie Akademie Ved Ceske Republiky (CZ) 1998-02-04 EP disclosed