Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738331 | 0.87 | CHRNB2 (0.51) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL676214 | 0.84 | CHRNB2 (0.59) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL11444309 | 0.83 | CHRNB2 (0.54) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL13096520 | 0.83 | CHRNB2 (0.54) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL674978 | 0.83 | CHRNB2 (0.54) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL19865697 | 0.79 | CHRNB2 (0.62) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL18089524 | 0.79 | CHRNB2 (0.61) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL675986 | 0.79 | CHRNB2 (0.67) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL13452380 | 0.79 | CHRNB2 (0.61) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL18801728 | 0.78 | CHRNB2 (0.49) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37781-E1 | VIRICIDES, PROTEASE INHIBITOR | DUPONT PHARMACEUTICALS COMPANY | 2002-07-02 | — | — | US | disclosed |