SCHEMBL7738337

SCHEMBL7738337

FC(F)(F)C(c1nc2ccccc2s1)(c1nc2ccccc2s1)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASR P41180 10/20 0.47
PSMB8 P28062 1/20 0.46
PSMB5 P28074 1/20 0.46
ALDH1A1 P00352 1/20 0.46
ADRA2A P08913 1/20 0.46
FBP1 P09467 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
DRD2 P14416 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
ADRA2B P18089 1/20 0.46
ADRA2C P18825 1/20 0.46
DRD1 P21728 1/20 0.46
MC5R P33032 1/20 0.46
OPRM1 P35372 1/20 0.46
DRD3 P35462 1/20 0.46
OPRK1 P41145 1/20 0.46
CCR2 P41597 1/20 0.46
HTR6 P50406 1/20 0.46
SLC6A3 Q01959 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1666355 0.84 CASR (0.50) CASRPSMB8PSMB5ALDH1A1ADRA2A
SCHEMBL28366070 0.81 CASR (0.45) CASRPSMB8PSMB5ALDH1A1ADRA2A
SCHEMBL28370247 0.80 CASR (0.44) CASRPSMB8PSMB5ALDH1A1ADRA2A
SCHEMBL28366681 0.79 CASR (0.43) CASRPSMB8PSMB5ALDH1A1ADRA2A
SCHEMBL5720317 0.78 CASR (0.51) CASRPSMB8PSMB5ALDH1A1ADRA2A
SCHEMBL227210 0.76 CASR (0.58) CASRALDH1A1ADRA2AFBP1ADORA3
SCHEMBL108180 0.76 CASR (0.58) CASRALDH1A1ADRA2AFBP1ADORA3
SCHEMBL3907554 0.76 CASR (0.53) CASRPSMB8PSMB5ALDH1A1ADRA2A
SCHEMBL7544923 0.73 CASR (0.64) CASRALDH1A1ADRA2AFBP1ADORA3
SCHEMBL30731332 0.72 CASR (0.57) CASRALDH1A1FBP1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1243043-A1 HIGH TEMPERATURE POLYBENZAZOLE AND POLYETHER ELECTROLYTES Sri International (US) 2002-09-25 EP disclosed
US-6176984-B1 HIGH TEMPERATURE POLYBENZAZOLE POLYMER ELECTROLYTE COMPRISES A BENZOBISOXAZOLE, A BENZOBISTHIAZOLE OR A BENZOBISIMIDAZOLE HOMO OR COPOLYMERS SRI INTERNATIONAL 2001-01-23 US disclosed
WO-2001001506-A1 HIGH TEMPERATURE POLYBENZAZOLE AND POLYETHER ELECTROLYTES SRI INTERNATIONAL (US) 2001-01-04 WO disclosed