Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 10/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | MC5R | P33032 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738337 | 0.84 | CASR (0.47) | CASRPIK3CGPSMB8PSMB5ALDH1A1 | |
| SCHEMBL28366070 | 0.81 | CASR (0.45) | CASRPIK3CGPSMB8PSMB5ALDH1A1 | |
| SCHEMBL5720317 | 0.81 | CASR (0.51) | CASRPSMB8PSMB5ALDH1A1ADRA2A | |
| SCHEMBL28370247 | 0.80 | CASR (0.44) | CASRPIK3CGPSMB8PSMB5ALDH1A1 | |
| SCHEMBL227210 | 0.79 | CASR (0.58) | CASRALDH1A1ADRA2AFBP1ADORA3 | |
| SCHEMBL3907554 | 0.79 | CASR (0.53) | CASRPSMB8PSMB5ALDH1A1ADRA2A | |
| SCHEMBL108180 | 0.79 | CASR (0.58) | CASRALDH1A1ADRA2AFBP1ADORA3 | |
| SCHEMBL28366681 | 0.78 | CASR (0.43) | CASRPIK3CGPSMB8PSMB5ALDH1A1 | |
| SCHEMBL7544923 | 0.76 | CASR (0.64) | CASRALDH1A1ADRA2AFBP1ADORA3 | |
| SCHEMBL6120718 | 0.75 | MIF (0.49) | ALDH1A1ALOX15HSD17B10TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119552155-A | Trifluoromethyl benzothiazole tertiary alcohol derivative and preparation method and application thereof | 河南农业大学 | 2025-03-04 | — | — | CN | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| US-4939140-A | ALDOSE REDUCTASE INHIBITORS | PFIZER INC. (US) | 1990-07-03 | — | — | US | claimed |
| US-20260132119-A1 | Alkylphenyl Substituted Compounds, Compositions and Methods of Use | DEEP APPLE THERAPEUTICS, INC. (US) | 2026-05-14 | — | — | US | disclosed |
| CN-119552155-B | Trifluoromethyl benzothiazole tertiary alcohol derivative and preparation method and application thereof | 河南农业大学 | 2025-11-04 | — | — | CN | disclosed |
| CN-119552155-B | Trifluoromethyl benzothiazole tertiary alcohol derivative and preparation method and application thereof | 河南农业大学 | 2025-11-04 | — | — | CN | disclosed |
| CN-119552155-A | Trifluoromethyl benzothiazole tertiary alcohol derivative and preparation method and application thereof | 河南农业大学 | 2025-03-04 | — | — | CN | disclosed |
| CN-119552155-A | Trifluoromethyl benzothiazole tertiary alcohol derivative and preparation method and application thereof | 河南农业大学 | 2025-03-04 | — | — | CN | disclosed |
| CN-119552155-A | Trifluoromethyl benzothiazole tertiary alcohol derivative and preparation method and application thereof | 河南农业大学 | 2025-03-04 | — | — | CN | disclosed |
| US-20250066344-A1 | BENZOTHIAZOLE, BENZOISOXAZOLE, AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2025-02-27 | — | — | US | disclosed |
| EP-4448500-A1 | BENZOTHIAZOLE, BENZOISOXAZOLE AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS | Bristol-Myers Squibb Company (US) | 2024-10-23 | — | — | EP | disclosed |
| US-7141596-B2 | Inhibitors of proteins that bind phosphorylated molecules | INCYTE CORPORATION (US) | 2006-11-28 | — | — | US | disclosed |
| CN-1760190-A | Method for preparing trifluoromethyl benzothiazole | UNIV SHANGHAI (CN) | 2006-04-19 | — | — | CN | disclosed |
| CN-1760190-A | Method for preparing trifluoromethyl benzothiazole | UNIV SHANGHAI (CN) | 2006-04-19 | — | — | CN | disclosed |
| US-20050272778-A1 | Inhibitors of proteins that bind phosphorylated molecules | INCYTE CORPORATION | 2005-12-08 | — | — | US | disclosed |
| EP-0565579-B1 | 2-IMINO 6-POLYFLUORALKYL 3-HETEROCYCLYLALKYL BENZOTHIAZOLINE DERIVATIVES, THEIR PREPARATION AND DRUGS CONTAINING SAME | RHONE POULENC RORER SA (FR) | 1994-07-20 | — | — | EP | disclosed |
| EP-0565579-A1 | 2-IMINO 6-POLYFLUORALKYL 3-HETEROCYCLYLALKYL BENZOTHIAZOLINE DERIVATIVES, THEIR PREPARATION AND DRUGS CONTAINING SAME. | RHONE POULENC RORER SA (FR) | 1993-10-20 | — | — | EP | disclosed |
| EP-0374040-B1 | 2-IMINO-BENZOTHIAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1993-03-24 | — | — | EP | disclosed |
| WO-1992012142-A1 | 2-IMINO 6-POLYFLUORALKYL 3-HETEROCYCLYLALKYL BENZOTHIAZOLINE DERIVATIVES, THEIR PREPARATION AND DRUGS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1992-07-23 | — | — | WO | disclosed |
| EP-0374040-A1 | 2-Imino-benzothiazoline derivatives, processes for their preparation and medicaments containing them | RHONE-POULENC SANTE (FR) | 1990-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272778-A1 | Inhibitors of proteins that bind phosphorylated molecules | PPP3CA, PPP5C, PPM1A | CASR 3633/4885PIK3CG 341/4885PSMB8 1288/4885 |
| US-20260132119-A1 | Alkylphenyl Substituted Compounds, Compositions and Methods of Use | GIPR, MC2R, GRPR | CASR 623/4885PIK3CG 1838/4885PSMB8 2182/4885 |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | STOM, SPOP, TTR | CASR 880/4885PIK3CG 1204/4885PSMB8 4668/4885 |
| US-20250066344-A1 | BENZOTHIAZOLE, BENZOISOXAZOLE, AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS | RXFP1, RXFP2, RXFP3 | CASR 963/4885PIK3CG 4335/4885PSMB8 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.