Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 14/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10614202 | 0.85 | ADORA2B (0.70) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL7738375 | 0.74 | ADORA2B (0.80) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL4291542 | 0.74 | ADORA2B (0.66) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL242409 | 0.73 | ADORA2B (0.56) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL10856890 | 0.73 | ADORA2B (0.61) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL10614407 | 0.73 | ADORA2B (0.71) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL7316494 | 0.72 | ADORA2B (0.76) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8872884 | 0.72 | ADORA2B (0.65) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL14267722 | 0.72 | ADORA2B (0.71) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL661108 | 0.71 | ADORA2B (1.00) | ADORA2BADORA2AKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708781-B1 | A 3 ADENOSINE RECEPTOR AGONISTS | USA (US) | 2001-10-04 | — | — | EP | disclosed |
| US-5773423-A | XANTHINE RIBOSIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-06-30 | — | — | US | disclosed |
| WO-1995002604-A1 | A3 ADENOSINE RECEPTOR AGONISTS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-01-26 | — | — | WO | disclosed |