Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738406 | 0.78 | NR1H2 (0.40) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7738435 | 0.71 | TAS1R3 (0.33) | ALDH1A1 | |
| SCHEMBL7739191 | 0.69 | NR1H2 (0.39) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7738390 | 0.68 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL7739187 | 0.67 | NR1H2 (0.39) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7739198 | 0.67 | NR1H2 (0.39) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7738394 | 0.66 | MEN1 (0.31) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7738387 | 0.66 | MEN1 (0.31) | MEN1ALDH1A1KMT2A | |
| SCHEMBL2525919 | 0.64 | CYP2D6 (0.43) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7738417 | 0.64 | MEN1 (0.39) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |