Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 12/20 | 0.63 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735671 | 0.90 | NISCH (0.74) | NISCHHTR1DADRA1APRMT1 | |
| SCHEMBL8196824 | 0.88 | NISCH (0.76) | NISCHHTR1DADRA1A | |
| SCHEMBL13135587 | 0.83 | NISCH (0.86) | NISCHPRMT1 | |
| Hydrochloric Acid SCHEMBL5562588 | 0.81 | NISCH (0.83) | NISCHPRMT1 | |
| SCHEMBL6824276 | 0.81 | PRMT1 (0.56) | NISCHHTR1DADRA1APRMT1 | |
| Hydrochloric Acid SCHEMBL7727877 | 0.80 | PRMT1 (0.55) | NISCHHTR1DADRA1APRMT1 | |
| Hydrochloric Acid SCHEMBL7727881 | 0.79 | NISCH (0.48) | NISCHHTR1DADRA1APRMT1 | |
| SCHEMBL11833135 | 0.78 | NISCH (1.00) | NISCHHTR1DADRA1A | |
| Benazoline SCHEMBL9575180 | 0.77 | NISCH (1.00) | NISCHPRMT1 | |
| Benazoline SCHEMBL29349712 | 0.77 | NISCH (1.00) | NISCHPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410562-B1 | ANTIDIABETIC AGENTS | ELI LILLY AND COMPANY | 2002-06-25 | — | — | US | disclosed |