Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 15/20 | 0.76 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 2/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738682 | 0.88 | NISCH (0.63) | NISCHHTR1DADRA1A | |
| SCHEMBL11833135 | 0.86 | NISCH (1.00) | NISCHHTR1DADRA1ALMNARECQL | |
| SCHEMBL8201787 | 0.80 | NISCH (0.62) | NISCH | |
| SCHEMBL7735671 | 0.80 | NISCH (0.74) | NISCHHTR1DADRA1A | |
| SCHEMBL5476725 | 0.78 | NISCH (0.79) | NISCHHTR1DADRA1ALMNARECQL | |
| SCHEMBL6824276 | 0.78 | PRMT1 (0.56) | NISCHHTR1DADRA1ARECQLTOP2A | |
| SCHEMBL22915140 | 0.77 | NISCH (0.81) | NISCHHTR1DADRA1ALMNARECQL | |
| Hydrochloric Acid SCHEMBL7727877 | 0.77 | PRMT1 (0.55) | NISCHHTR1DADRA1ARECQLTOP2A | |
| Hydrochloric Acid SCHEMBL7727881 | 0.76 | NISCH (0.48) | NISCHHTR1DADRA1ALMNARECQL | |
| Hydrochloric Acid SCHEMBL7736302 | 0.76 | NISCH (0.48) | NISCHHTR1DADRA1ALMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |