Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.70 |
| ▸ | CA2 | P00918 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738854 | 1.00 | CA1 (0.70) | CA1CA2MAPTKMT2AKDM4E | |
| SCHEMBL269558 | 0.89 | CA1 (0.88) | CA1CA2MAPTKMT2AKDM4E | |
| SCHEMBL16604876 | 0.89 | CA1 (0.88) | CA1CA2MAPTKMT2AKDM4E | |
| SCHEMBL3001548 | 0.88 | CA1 (0.72) | CA1CA2MAPTKMT2AKDM4E | |
| SCHEMBL69268 | 0.86 | PTPN11 (0.69) | CA1CA2MAPTKMT2AKDM4E | |
| SCHEMBL7738912 | 0.85 | CA1 (0.69) | CA1CA2MAPTKDM4EPTPN11 | |
| SCHEMBL13139895 | 0.85 | TDP1 (0.69) | CA1CA2MAPTKMT2AKDM4E | |
| SCHEMBL13139896 | 0.85 | TDP1 (0.69) | CA1CA2MAPTKMT2AKDM4E | |
| SCHEMBL7738900 | 0.85 | CA1 (0.69) | CA1CA2MAPTKDM4EPTPN11 | |
| SCHEMBL20252721 | 0.84 | CA1 (0.60) | CA1CA2MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |