SCHEMBL69268

SCHEMBL69268

COC(=O)c1ccc(C#Cc2ccc(C(=O)OC)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 1/20 0.69
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
CA12 O43570 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA14 Q9ULX7 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
MAPT P10636 4/20 0.59
TSHR P16473 2/20 0.58
ALDH1A1 P00352 2/20 0.55
LOXL2 Q9Y4K0 1/20 0.53
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
RAB9A P51151 2/20 0.52
HPGD P15428 2/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1535874 0.94 PTPN11 (0.63) PTPN11CA1CA2CA12CA7
SCHEMBL1105504 0.92 TSHR (0.67) PTPN11CA1CA2CA12CA7
SCHEMBL16140276 0.92 TDP1 (0.77) PTPN11CA1CA2CA12CA7
SCHEMBL10412465 0.91 PTPN11 (0.60) PTPN11CA1CA2CA12CA7
SCHEMBL24230270 0.90 KMT2A (0.62) PTPN11CA1CA2CA12CA7
SCHEMBL254229 0.90 PTPN11 (0.59) PTPN11CA1CA2CA12CA7
SCHEMBL20764570 0.90 PTPN11 (0.59) PTPN11CA1CA2CA12CA7
SCHEMBL20252721 0.90 CA1 (0.60) PTPN11CA1CA2CA12CA7
SCHEMBL8272575 0.90 PTPN11 (0.58) PTPN11CA1CA2CA12CA7
SCHEMBL22953995 0.89 PTPN11 (0.58) PTPN11CA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220185963-A1 A CRYSTALLINE, TWO DIMENSIONAL POLYMERS AND A PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2022-06-16 US disclosed
EP-3940013-A1 GRAPHENE NANORIBBON AND METHOD FOR PRODUCING SAME Taoka Chemical Co., Ltd. (JP) 2022-01-19 EP disclosed
WO-2020202213-A1 A CRYSTALLINE, TWO DIMENSIONAL POLYMERS AND A PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2020-10-08 WO disclosed
US-9263683-B2 Use of cobalt complexes for preparing an active layer in a photovoltaic cell, and corresponding photovoltaic cell CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2016-02-16 US disclosed
EP-2691404-B1 USE OF COBALT COMPLEXES FOR THE PREPARATION OF THE ACTIVE LAYER OF A PHOTVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL CENTRE NAT RECH SCIENT (FR) 2015-05-06 EP disclosed
EP-2691404-B1 USE OF COBALT COMPLEXES FOR THE PREPARATION OF THE ACTIVE LAYER OF A PHOTVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL CENTRE NAT RECH SCIENT (FR) 2015-05-06 EP disclosed
US-20140290745-A1 USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) 2014-10-02 US disclosed
US-20140290745-A1 USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) 2014-10-02 US disclosed
EP-2691404-A1 USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL Centre National De La Recherche Scientifique (FR) 2014-02-05 EP disclosed
WO-2012131257-A1 USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2012-10-04 WO disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220185963-A1 A CRYSTALLINE, TWO DIMENSIONAL POLYMERS AND A PROCESS FOR THE PREPARATION THEREOF CSPP1, PCBP1, FKBP2 PTPN11 3571/4885CA1 973/4885CA2 1957/4885
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 PTPN11 3108/4885CA1 550/4885CA2 612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.