SCHEMBL7738889

SCHEMBL7738889

Oc1ccc(-c2ccc(O)c(O)c2)c(O)c1

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.62
APP P05067 3/20 0.60
MIF P14174 1/20 0.49
XDH P47989 1/20 0.49
MAPT P10636 2/20 0.48
ESR2 Q92731 2/20 0.48
ESR1 P03372 1/20 0.47
SNCA P37840 2/20 0.47
CD38 P28907 1/20 0.46
HSD17B1 P14061 1/20 0.46
HSD17B2 P37059 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25421370 0.86 ALOX5 (0.62) ALOX5APPMIFXDHMAPT
SCHEMBL278379 0.82 ALOX5 (0.73) ALOX5ESR2ESR1HSD17B1HSD17B2
SCHEMBL33527 0.82
SCHEMBL4862349 0.82 ALOX5 (0.60) ALOX5APPMIF
SCHEMBL29829218 0.82
SCHEMBL10097918 0.80 ESR2 (0.53) ALOX5MAPTESR2ESR1HSD17B1
SCHEMBL3811869 0.80 ALOX5 (0.70) ALOX5ESR2ESR1HSD17B1HSD17B2
SCHEMBL31419103 0.79 ESR2 (0.74) ALOX5ESR2ESR1HSD17B1HSD17B2
SCHEMBL28819464 0.79 ESR2 (0.74) ALOX5ESR2ESR1HSD17B1HSD17B2
SCHEMBL29666588 0.79 ESR2 (0.74) ALOX5ESR2ESR1HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115266282-A Pathological image automatic identification method based on combination of three methods of HE staining, ki67 and P16 武汉兰丁云医学检验实验室有限公司 2022-11-01 CN claimed
CN-116998459-A Immunodeficient mice expressing human interleukin 15 杰克逊实验室 2023-11-07 CN disclosed
US-20230201226-A1 COMBINATION THERAPY FOR REDUCING DRUG-INDUCED NEPHROTOXICITY, DYSLIPIDEMIA AND HYPERGLYCEMIA YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2023-06-29 US disclosed
CN-115266282-A Pathological image automatic identification method based on combination of three methods of HE staining, ki67 and P16 武汉兰丁云医学检验实验室有限公司 2022-11-01 CN disclosed
CN-113180007-B Exudative animal pneumonia model construction method 扬州大学 2022-08-19 CN disclosed
CN-114671844-A Method for separating and preparing 4-O-methyl hematoxylin 浙江工业大学 2022-06-28 CN disclosed
CN-102861338-A Combinations of comprising a bcr-abl, c-kit and pdgf-r tyrosine kinase inhibitor used for treating cancer NOVARTIS AG 2013-01-09 CN disclosed
EP-1064313-A4 SELECTED HIGH THERMAL NOVOLAKS AND POSITIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS ARCH SPEC CHEM INC (US) 2001-06-13 EP disclosed
EP-1064313-A1 SELECTED HIGH THERMAL NOVOLAKS AND POSITIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS ARCH SPECIALTY CHEMICALS, INC. (US) 2001-01-03 EP disclosed
US-5985507-A PHOTORESISTS WITH THERMAL PROPERTIES OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1999-11-16 US disclosed
WO-1999042507-A1 SELECTED HIGH THERMAL NOVOLAKS AND POSITIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1999-08-26 WO disclosed
US-5674657-A PHENOLIC RESIN COPOLYMER COMPRISING META-CRESOL, PARA-CRESOL AND OTHER PHENOLIC MONOMER SELECTED FROM XYLENOLS, METHOXYPHENOLS; RADIATION SENSITIVITY OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1997-10-07 US disclosed