SCHEMBL773898

SCHEMBL773898

CCO[Si](CCCC1CNCCO1)(OCC)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 12/20 0.42
SLC6A2 P23975 10/20 0.42
SLC6A3 Q01959 8/20 0.42
HTR2A P28223 3/20 0.42
ADRB2 P07550 2/20 0.42
HTR1A P08908 1/20 0.42
ADRA1A P35348 1/20 0.42
HTR2B P41595 1/20 0.42
ADRA2C P18825 1/20 0.36
EPHX1 P07099 1/20 0.32
MLNR O43193 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2C P28335 1/20 0.32
OPRK1 P41145 1/20 0.32
KCNH2 Q12809 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28862352 0.95 SLC6A4 (0.41) SLC6A4SLC6A2SLC6A3HTR2AADRB2
SCHEMBL27943210 0.90 SLC6A4 (0.38) SLC6A4SLC6A2SLC6A3HTR2AADRB2
SCHEMBL16714747 0.88 SLC6A2 (0.42) SLC6A4SLC6A2SLC6A3HTR2AADRB2
SCHEMBL776321 0.88 SLC6A2 (0.42) SLC6A4SLC6A2SLC6A3HTR2AADRB2
SCHEMBL27947169 0.85 SLC6A2 (0.40) SLC6A4SLC6A2SLC6A3HTR2AADRB2
SCHEMBL776671 0.84 ADRA2C (0.43) SLC6A4SLC6A2SLC6A3HTR2AADRB2
SCHEMBL2409155 0.81 SLC6A4 (0.46) SLC6A4SLC6A2SLC6A3HTR2AADRB2
SCHEMBL3031245 0.80 EPHX1 (0.50) EPHX1ALDH1A1
SCHEMBL27943176 0.79 SLC6A2 (0.37) SLC6A4SLC6A2SLC6A3HTR2AADRB2
SCHEMBL775084 0.78 ADRA2C (0.40) SLC6A4SLC6A2SLC6A3HTR2AADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9862812-B2 Composition containing nitrogen-containing organoxysilane compound and method for making the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
EP-2876111-B1 Composition containing nitrogen-containing organoxysilane compound and method for making the same SHINETSU CHEMICAL CO (JP) 2017-09-20 EP disclosed
EP-2876111-A1 Composition containing nitrogen-containing organoxysilane compound and method for making the same Shin-Etsu Chemical Co., Ltd. (JP) 2015-05-27 EP disclosed
US-20150135996-A1 COMPOSITION CONTAINING NITROGEN-CONTAINING ORGANOXYSILANE COMPOUND AND METHOD FOR MAKING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-21 US disclosed
US-8361176-B2 Hydrophilic and hydrophobic silane surface modification of abrasive grains SAINT-GOBAIN ABRASIVES, INC. (US) 2013-01-29 US disclosed
EP-1907517-B1 AMINE TUNGSTATES AND DIARYLAMINES IN LUBRICANT COMPOSITIONS KING INDUSTRIES INC (US) 2012-12-05 EP disclosed
US-20120066980-A1 Hydrophilic and Hydrophobic Silane Surface Modification of Abrasive Grains SAINT-GOBAIN ABRASIFS (FR) 2012-03-22 US disclosed
US-8080500-B2 Amine tungstates and lubricant compositions KING INDUSTRIES, INC. (US) 2011-12-20 US disclosed
US-8021449-B2 Hydrophilic and hydrophobic silane surface modification of abrasive grains SAINT-GOBAIN ABRASIVES, INC. (US) 2011-09-20 US disclosed
US-7820602-B2 Amine tungstates and lubricant compositions KING INDUSTRIES, INC. (US) 2010-10-26 US disclosed
US-20090260297-A1 Hydrophilic and hydrophobic silane surface modification of abrasive grains SAINT-GOBAIN ABRASIFS (FR) 2009-10-22 US disclosed
US-20090029888-A1 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS KING INDUSTRIES, INC. 2009-01-29 US disclosed
US-20080194440-A1 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS RAVICHANDRAN RAMANATHAN 2008-08-14 US disclosed
EP-1907517-A2 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS King Industries, Inc. (US) 2008-04-09 EP disclosed
US-20070042917-A1 Amine Tungstates and Lubricant Compositions KING INDUSTRIES, INC. 2007-02-22 US disclosed
WO-2007009022-A2 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS KING INDUSTRIES, INC. (US) 2007-01-18 WO disclosed