Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16756208 | 0.88 | ALOX15 (0.59) | ALOX15LMNAMAPTTSHRKDM4E | |
| SCHEMBL18887952 | 0.83 | ESR1 (0.54) | ALOX15GAAJAK2MAPTCA1 | |
| SCHEMBL4084650 | 0.81 | MAPT (0.54) | ALOX15LMNAMAPTCA1CA2 | |
| SCHEMBL21598307 | 0.81 | TDP1 (0.54) | ALOX15KDM4EALDH1A1HTTHPGD | |
| SCHEMBL15548138 | 0.81 | ALOX15 (0.53) | ALOX15LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL23318134 | 0.81 | ALOX15 (0.45) | ALOX15CA1CA2ALDH1A1HTT | |
| SCHEMBL15548518 | 0.81 | ALOX15 (0.53) | ALOX15MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL361508 | 0.81 | GAA (0.50) | ALOX15GAAJAK2LMNAMAPT | |
| SCHEMBL688269 | 0.80 | GAA (0.54) | GAAJAK2LMNAMAPTCA1 | |
| SCHEMBL688754 | 0.80 | GAA (0.54) | GAAJAK2LMNAMAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1145633-C | Hydroformylation using multidentate phosphite ligands | ��Ļ���Ű˾ | 2004-04-14 | — | — | CN | disclosed |
| CN-1374965-A | Hydroformylation using multidentate phosphite ligands | DU PONT (US) | 2002-10-16 | — | — | CN | disclosed |
| US-6399534-B2 | CATALYTIC HYDROFORMYLATION | E. I. DU PONT DE NEMOURS AND COMPANY (DE) | 2002-06-04 | — | — | US | disclosed |