Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.56 |
| ▸ | MAOA | P21397 | 11/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960175 | 0.85 | MAOB (0.55) | MAOBMAOANPC1RAB9ATDP1 | |
| SCHEMBL9498221 | 0.78 | NQO1 (0.46) | TDP1CA12CA1CA2CA7 | |
| SCHEMBL3920063 | 0.76 | MAOB (0.51) | MAOBMAOANPC1RAB9ATDP1 | |
| SCHEMBL3654095 | 0.76 | ERN1 (0.48) | — | |
| SCHEMBL29793157 | 0.76 | ERN1 (0.48) | — | |
| SCHEMBL13214879 | 0.75 | ALDH1A1 (0.46) | MAOBMAOANPC1RAB9ACA12 | |
| SCHEMBL20767500 | 0.75 | MAOB (0.56) | MAOBMAOANPC1RAB9A | |
| SCHEMBL14154468 | 0.74 | APP (0.67) | MAOBMAOAAPPRXRARXRB | |
| SCHEMBL580259 | 0.74 | KDM4E (0.45) | NPC1RAB9ATDP1 | |
| SCHEMBL865744 | 0.73 | MAOB (0.67) | MAOBMAOAAPPRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |