Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 17/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.68 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4920484 | 0.94 | OPRL1 (0.76) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL6582318 | 0.92 | OPRL1 (0.79) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL4909922 | 0.89 | OPRL1 (0.73) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL6589497 | 0.87 | OPRL1 (0.76) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL4909291 | 0.85 | OPRL1 (0.79) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL4915159 | 0.83 | OPRL1 (0.85) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL6589245 | 0.83 | OPRL1 (0.79) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL4919105 | 0.83 | OPRL1 (0.85) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL7739346 | 0.82 | OPRL1 (0.73) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL4918155 | 0.82 | OPRL1 (0.82) | OPRL1OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |