Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 18/20 | 0.79 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.79 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.79 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7739344 | 0.92 | OPRL1 (0.68) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL6589497 | 0.90 | OPRL1 (0.76) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL4919105 | 0.90 | OPRL1 (0.85) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL4921253 | 0.88 | OPRL1 (0.81) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL4921256 | 0.88 | OPRL1 (0.81) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| SCHEMBL6585745 | 0.88 | OPRL1 (0.81) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| J-113,397 SCHEMBL29623041 | 0.88 | OPRL1 (1.00) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| J-113,397 SCHEMBL875219 | 0.88 | OPRL1 (1.00) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| J-113,397 SCHEMBL6586337 | 0.88 | OPRL1 (1.00) | OPRL1OPRM1OPRK1OPRD1DRD2 | |
| J-113,397 SCHEMBL4920647 | 0.88 | OPRL1 (1.00) | OPRL1OPRM1OPRK1OPRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |