SCHEMBL7739423

SCHEMBL7739423

[O]C1Sc2ccccc2S1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.36
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32
BCHE P06276 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
POLB P06746 1/20 0.32
CYP3A4 P08684 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
MAOA P21397 1/20 0.32
CNR1 P21554 1/20 0.32
ACHE P22303 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12264200 0.73 IDO1 (0.39) IDO1BRD4CREBBPBCHEMEN1
SCHEMBL7028419 0.69 IDO1 (0.36) IDO1BCHEMEN1CYP1A2POLB
SCHEMBL2931874 0.69 MEN1 (0.36) IDO1BRD4CREBBPBCHEMEN1
SCHEMBL3067264 0.69 IDO1 (0.46) IDO1BCHEMEN1CYP1A2POLB
SCHEMBL11982524 0.69 IDO1 (0.36) IDO1BCHEMEN1CYP1A2POLB
SCHEMBL7022756 0.69 IDO1 (0.36) IDO1BCHEMEN1CYP1A2POLB
SCHEMBL9492639 0.67 MAPT (0.39) BCHEMEN1POLBCYP3A4MAPT
SCHEMBL460002 0.67 IDO1 (0.34) IDO1BCHEMEN1CYP1A2POLB
SCHEMBL5909432 0.67 IDO1 (0.34) IDO1BCHEMEN1CYP1A2POLB
SCHEMBL29475406 0.67 IDO1 (0.34) IDO1BCHEMEN1CYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410748-B1 Alicycli c group-containing monomer KABUSHIKI KAISHA TOSHIBA (JP) 2002-06-25 US disclosed
US-6291129-B1 LIGHT SENSITIVE ELEMENT WITH UNSATURATED POLYMERS KABUSHIKI KAISHA TOSHIBA (JP) 2001-09-18 US disclosed